Ibuprofen may help lower Parkinson's risk

Study suggests people who take the pain reliever regularly cut their risk of the disease by 40%

Rachit Mankad

Posted On Wednesday, March 03, 2010   

The common anti-inflammatory drug, ibuprofen, may hold key to staving off Parkinson's.

In a Harvard study, people who took 3 or more tablets a week showed a 40% lower risk than those who didn't take the common pain reliever.

Researchers analysed data on 1,36,474 people who did not have Parkinson's at the start of the study. In a 6-year span, 293 were diagnosed with the disease. Those who took the largest doses of ibuprofen were less likely to have developed Parkinson's than were those who took smaller amounts of the drug, the study found.

No other pain reliever was found to lower the risk for Parkinson's.

Study author Dr Xiang Gao, an instructor and epidemiologist at Harvard Medical School and Brigham and Women's Hospital in Boston, said the findings are important for anyone at increased risk for Parkinson's because most people with the disease eventually become severely disabled.

"There is thus a need for better preventive interventions," Gao said. "In this context, our findings regarding the potential neuroprotective effect of ibuprofen, one of the most commonly used analgesics, on Parkinson's disease may have important public health and clinical implications."

Parkinson's is a disease that affects nerve cells in the brain that control the movement of muscles. It affects millions worldwide, men far more often than women. The exact cause is unknown, but experts believe it's a combination of genetic and environmental factors.

Gao said that though the drug levodopa is the current standard treatment for Parkinson's, much more is needed.

Pic: Niels Timmer



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